Center for Blood Oxygen Transport & Hemostasis (CBOTH)

Nanofabrication and Characterization Core

The Nanofabrication and Characterization Core Labs provide state-of-the-art facilities, training and services to the UMB research community, collaborators, and industrial partners/users. These shared-user facilities provide direct access to specialized research equipment operated by expert staff with advanced degrees in science and engineering.

Strategically located within the CBOTH facilities and in downtown Baltimore, the Core Lab offers integrated solutions in nanoparticle synthesis, physico-chemical characterization, wet-chemistry support, drug release studies, stability studies, nanoparticle tracking analysis, and electrophoretic potential measurements. Our state-of-the-art capabilities will support rapid in vitro measurement of aqueous state synthetic (e.g. liposomes, gold nanoparticles) or biological nanoparticles (e.g. extracellular vesicles) through multiple physical parameters such as size, concentration, surface charge, and phenotype characteristics.

Regina Adão
Director, CBOTH Nanofabrication and Characterization Core
410-706-4531  radao@som.umaryland.edu 

Red Blood Cell and Hematology Core

The Red Blood Cell (RBC) Physiology and Hemostasis Core is designed to facilitate research related to RBC function/performance and blood component biology. Our mission is to provide access to cutting edge technology and world class expertise to answer fundamental research questions related to blood and hemodynamic function in health and disease.

The RBC Physiology and Hemostasis Core offers unique resources to CBOTH investigators and Collaborators (within the University of Maryland Medical System). The services provided by the Core allow evaluation of RBC biochemistry, morphology, physiology, and biophysics, and their effect on vascular regulation and O2 delivery.

Stephen Rogers, PhD
Director, CBOTH Red Blood Cell and Hematology Core
410-706-7094  stephen.rogers@som.umaryland.edu

Small Animal Surgery and Physiology Core

The Small Animal Surgery and Physiology (SASP) core resource primarily supports experimental models that focus on (but not be limited to) cardio-pulmonary and vascular physiology and oxygen transport at the whole organism, isolated organ and tissue level. Significant experience and technical mastery in small animal surgical preparations (rodent, hamster, rabbit). The SASP core supports 8-10 CBOTH PIs and serve as a consultant in protocol design and IACUC submission as well as support each stage of experimental preparation and data analysis. The core is fully equipped with a full array of state-of-the-art anesthetic and surgical instrumentation. 

Qihong Wang, MD, MsC
Director, CBOTH SASP Core
410-706-6079  Qihong.Wang@som.umaryland.edu 

Links and Resources

1. Nanofabrication and Characterization Core Website

2. Red Blood Cell and Hematology Core Website

3. Small Animal Surgery and Physiology Core Website

Contacts